Publications

 

For each publication, click on the title for more information, including the abstract, complete citation, and access to the article. You will be redirected to the National Library of Medicine.

 

 

PubMed

Discovery and Preliminary SAR of Arylpiperazines as Novel, Brainpenetrant Antiprion Compounds.
Li Z
Gever J
Rao S
Widjaja K
Prusiner SB
Silber BM
2-Aminothiazoles with improved pharmacotherapeutic properties for treatment of prion disease.
Li Z
Silber BM
Rao S
Gever JR
Bryant C
Gallardo-Godoy A
Dolghih E
Widjaja K
Elepano M
Jacobson MP
Prusiner SB
Renslo AR
Plasma membrane invaginations containing clusters of full-length PrPSc are an early form of prion-associated neuropathology in vivo.
Godsave SF
Wille H
Pierson J
Prusiner SB
Peters PJ
Antiprion compounds that reduce PrP(Sc) levels in dividing and stationary-phase cells.
Silber BM
Gever JR
Li Z
Gallardo-Godoy A
Renslo AR
Widjaja K
Irwin JJ
Rao S
Jacobson MP
Ghaemmaghami S
Prusiner SB
Notch-1 activation and dendritic atrophy in prion disease.
Ishikura N
Clever JL
Bouzamondo-Bernstein E
Samayoa E
Prusiner SB
Huang EJ
DeArmond SJ
Structure-activity relationship study of 9-aminoacridine compounds in scrapie-infected neuroblastoma cells.
May BC
Witkop J
Sherrill J
Anderson MO
Madrid PB
Zorn JA
Prusiner SB
Cohen FE
Guy RK
Discovery of 2-aminothiazoles as potent antiprion compounds.
Ghaemmaghami S
May BC
Renslo AR
Prusiner SB
Transmission of elk and deer prions to transgenic mice.
Tamgüney G
Giles K
Bouzamondo-Bernstein E
Bosque PJ
Miller MW
Safar J
DeArmond SJ
Prusiner SB
Directed evolution of an anti-prion protein scFv fragment to an affinity of 1 pM and its structural interpretation.
Luginbühl B
Kanyo Z
Jones RM
Fletterick RJ
Prusiner SB
Cohen FE
Williamson RA
Burton DR
Plückthun A
Discovering DNA encodes heredity and prions are infectious proteins.
Prusiner SB
McCarty M
Continuum of prion protein structures enciphers a multitude of prion isolate-specified phenotypes.
Legname G
Nguyen HO
Peretz D
Cohen FE
DeArmond SJ
Prusiner SB
Structure-activity relationship study of prion inhibition by 2-aminopyridine-3,5-dicarbonitrile-based compounds: parallel synthesis, bioactivity, and in vitro pharmacokinetics.
May BC
Zorn JA
Witkop J
Sherrill J
Wallace AC
Legname G
Prusiner SB
Cohen FE