Edited by Dr. Stanley Prusiner, Prion Biology and Prion Diseases is the most comprehensive reference collection on prions to date, with contributions from over 120 authors across the field. These volumes have been greatly expanded from the previous book, Prion Biology and Diseases, published in 2004, and extensively discuss the evolving knowledge and increasing role of various prions in human health and disease. These essential volumes are available from Cold Spring Harbor Laboratory Press and Amazon.
Thank you to the many contributors, who have brought this vast work to fruition.
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 Congratulations to Jeremy Willsey, who received a UCSF Weill Institute for Neurosciences 2017 Trailblazer Award for his proposal titled “Identifying Convergent Molecular Networks in Autism.” The Trailblazer Award Program supports creative, high-risk/high-reward research projects in the neurosciences with the ultimate goal of helping patients by achieving greater understanding of the human brain in health and disease.
CRISPR-based genetic screens are a powerful technology to elucidate disease mechanisms and identify potential therapeutic strategies. However, the experimental design of a successful screen remains a challenge. Graduate student Tamas Nagy and IND faculty Dr. Martin Kampmann developed a simulation tool for these screens, termed CRISPulator, which helps researches to optimize the experimental parameters of different types of CRISPR-based screens. CRISPulator helped to uncover new rules for optimal screen design. The research was published in an article in BMC Bioinformatics:... Read more ...
He was recognized for his contributions to the development of innovative genetic screening technologies in mammalian cells and their application to identify the target of new drugs. Dr. Kampmann describes this research in a feature article in the same issue (Kampmann, M. [2017] Elucidating drug targets and mechanisms of action by genetic screens in mammalian cells. Chemical Communications 53: 7162–7167... Read more ... Pages |
IND faculty Martin Kampmann was