Staff Research Associate I/II – Kampmann Lab
In the Staff Research Associate I/II (SRA I/II) position you would be an integral member of the Kampmann lab at the UCSF Institute for Neurodegenerative Diseases (IND). The Kampmann lab develops and uses innovative technologies to understand cellular and molecular mechanisms of human diseases and to discover new therapeutic strategies. A major focus of our research is on neurodegenerative diseases such as Alzheimer’s and Parkinson’s Disease. To this end, we have established a CRISPR-based functional genomics platform for genetic screens in human iPSC-based models of disease (Tian et al., 2019; Neuron). Our lab is part of the UCSF research community, the Chan Zuckerberg Biohub, the Chan Zuckerberg Neurodegeneration Challenge Network, the Tau Consortium and other collaborative research groups, providing us with an outstanding network of collaborators and access to other cutting-edge technologies. We are an interdisciplinary group of postdocs, graduate students and staff research associates. We are proud of our lab culture of intellectual curiosity, collaboration, support, diversity, and fun! Read more about our lab at kampmannlab.ucsf.edu.
In this position, you will be working as a member of a research team developing innovative, CRISPR/Cas9-based functional genomics approaches to understand the disease mechanism and to identify potential therapeutic strategies. You must be willing to work in a team, be organized, enjoy problem solving, and have strong communication skills. As you become familiar with our methodology, there will be opportunities to work independently on research projects. Based on your interest and expertise, you will be able to contribute to bioinformatics analysis of data as well. Past staff research associates have been integral co-authors on high impact publications in the lab.
Responsibilities include experiments based on mammalian cell culture (including iPSCs and iPSC-derived neurons and glia), molecular biology (including construction of DNA vectors, and qPCR), preparation of samples for next-generation sequencing, performing flow cytometry, biochemistry, functional assays, imaging, performing basic statistical calculations, and other duties as assigned. No more than 20% of the time will be spent on lab management tasks, such as glass washing, autoclaving, preparing and aliquoting buffers and media, pouring bacterial plates, cleaning of waterbaths, accepting deliveries, checking inventory.
The Institute for Neurodegenerative Diseases (IND) at UCSF is pursuing a cutting-edge blend of basic science and clinical medicine to provide outstanding care to those suffering from neurodegenerative diseases. Founded in 1999, the IND is committed to creating therapeutics that will halt diseases such as Alzheimer’s, Parkinson’s, Creutzfeldt-Jakob disease and dementia resulting from traumatic brain injuries. The IND is poised to make serious contributions to this struggle at the frontier of neuroscience and medicine. The mission of the Institute for Neurodegenerative Diseases is to discover causes and develop cures for these illnesses with an innovative program of basic research and clinical medicine.
The University of California, San Francisco (UCSF) is a leading university dedicated to promoting health worldwide through advanced biomedical research, graduate-level education in the life sciences and health professions, and excellence in patient care. It is the only campus in the 10-campus UC system dedicated exclusively to the health sciences. We bring together the world’s leading experts in nearly every area of health. We are home to five Nobel laureates who have advanced the understanding of cancer, neurodegenerative diseases, aging and stem cells.
UCSF is a diverse community made of people with many skills and talents. We seek candidates whose work experience or community service has prepared them to contribute to our commitment to professionalism, respect, integrity, diversity and excellence – also known as our PRIDE values. The University of California San Francisco is an Equal Opportunity/Affirmative Action Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, age, protected veteran or disabled status, or genetic information.