Kampmann Lab Postdoc John Chen Named Longevity Fellow
Dr. John Chen, postdoctoral fellow in the Kampmann lab at the IND, won a QB3/Calico Longevity Fellowship. Dr. Chen works with Diane Nathaniel in the Kampmann lab to uncover cellular pathways controlling aggregation and prion-like spread of the protein tau, which is associated with Alzheimer’s disease, frontotemporal dementia, and other neurodegenerative diseases. The team is using an innovative, CRISPR-based functional genomics approach co-developed by Dr. Kampmann. The funding from the QB3/Calico program will support the implementation of these experiments in human iPSC-derived neurons. Pathways identified in this research may guide the development of new therapeutics for AD, FTD, and other neurodegenerative diseases.