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Stepahnie See, Graduate Student, Kampmann and Gestwicki Labs |
Stephanie See, a PhD student in the Kampmann and Gestwicki labs at the IND, was awarded the prestigious National Defense Science & Engineering Graduate (NDSEG) Fellowship. Stephanie's research is focused on the cellular mechanisms controlling the aggregation and prion-like spread of the protein alpha-synuclein, which is associated with Parkinson's disease and other neurodegenerative diseases. Her interdisciplinary project combines two innovative approaches: (1) the CRISPR/Cas9-based genetic screening technology, co-developed by IND faculty Dr. Martin Kampmann, and (2) a biochemical platform to investigate interactions with molecular chaperones, established by IND faculty Dr. Jason Gestwicki. The results from Stephanie’s research have the potential to reveal new therapeutic strategies for neurodegenerative diseases associated with alpha-synuclein aggregation.