Zuzana Krejciova, PhD

Postdoctoral Scholar, Prusiner Lab

Zuzana Krejciova received her Ph.D. in 2012 from the National CJD Research & Surveillance Unit, Centre for Clinical Brain Sciences at the University of Edinburgh, United Kingdom. Under the supervision of Dr. Mark W. Head, her Ph.D. project was concerned with the investigation of the potential susceptibility of human lymphoreticular FDC-like cells and hESC to prion propagation in vitro. In her postdoctoral research at the same institution, Zuzana focused on the possible threat to human health posed by BSE in sheep, which she studied by modeling the serial passage of the sheep BSE agent in vitro using PMCA. She also investigated the role of the differentiated state in determining susceptibility of human cells to human prion infection by implicating neurons and astrocytes differentiated from human embryonic stem cells or induced pluripotent stem cells to abnormal prion propagation in vitro.

Dr. Krejciova joined the Prusiner laboratory in September 2014 as a postdoctoral scholar and continues to tackle cell susceptibility to prion infection in vitro and explore the causes and underlying molecular pathways in neurodegenerative diseases. She is also interested in the development of long-awaited and unambiguously needed prophylaxis and effective drug treatments for prion diseases.

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